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AKTA pure – The Flexible Standard for Laboratories

The AKTA pure™ is a leading liquid chromatography system designed by Cytiva for the reliable purification of proteins, peptides, and nucleic acids on a laboratory scale. Available in several configurations (pure 25, pure 150, pure micro), it offers a flow rate range of up to 150 mL/min and an operating pressure of up to 200 bar, with an accuracy of less than 0.5% RSD. Its modular design, featuring over 20 hardware options, and its column selection valve enable rapid screening tailored to multi-user environments. Its micro version, with enhanced resolution, is particularly well-suited for upstream protocols in cryo-EM applications. Controlled via UNICORN™ software, it ensures full traceability of your purification results. BPM TechCare provides preventive and corrective maintenance for your AKTA pure in Switzerland to ensure the longevity of your system.

Recognized flexibility in a multi-user environment

The AKTA pure stands out for its modular design: with more than 20 hardware options, the system can be adapted to applications ranging from standard purification to antibody purification and column screening. It adapts to the evolving needs of a shared laboratory with multiple users and protocols.

Technical Specifications

Features AKTA™ Pure Details
Flow rate range 0.001 to 25 mL/min (pure 25) or up to 150 mL/min (pure 150); can be extended to 50 mL/min for column packing
Operating pressure Up to 200 bar (20 MPa)
Control Software UNICORN™ (integrated controller + computer interface)
Flow Rate Accuracy RSD < 0.5%
Detection Multi-wavelength UV (up to 3 wavelengths simultaneously), pH, conductivity
Modularity More than 20 hardware options; micro version available for cryo-EM applications

Precision designed for your critical results

Thanks to its column selection valve and upstream/downstream pressure sensors, the AKTA pure ensures enhanced operational safety and continuous monitoring of the pressure differential across the resin bed. When paired with the multi-wavelength UV monitor, it ensures reliable detection, even for samples with low concentrations.

Column Selection Valve (V9-C)

Connect multiple columns simultaneously to perform rapid screening and identify the resin best suited for your application, without having to manually reconfigure the system.

Dedicated sample pump

A dedicated sample injection pump ensures optimal reproducibility, regardless of the volume or viscosity of your sample.

Multi-wavelength UV Detection

The U9-M monitor allows you to track multiple wavelengths simultaneously, enabling you to distinguish between low and high protein concentrations within the same run.

Micro version for cutting-edge applications

The AKTA Pure Micro offers enhanced resolution and sharper peaks, making it particularly well-suited for purification protocols prior to cryo-electron microscopy (cryo-EM) applications.

Why invest in AKTA Pure?

Flexibility for Future Growth

With more than 20 hardware options, the system adapts to changes in your protocols without requiring a complete replacement.

Reproducible accuracy

Flow rate accuracy of less than 0.5% RSD ensures the reliability of your results, run after run.

Operational Safety

Continuous monitoring of the inlet and outlet pressure protects your column and resin from accidental overpressure.

Versatility in Applications

From column screening to antibody purification, including cryo-EM applications with the micro version, a single system covers most of your laboratory needs.

BPM TechCare, your AKTA-certified expert in Switzerland

Maximize the lifespan of your chromatography system with our specialized AKTA maintenance service. Whether you need assistance with a critical installation, thorough preventive maintenance, or rapid troubleshooting, our team ensures the longevity and performance of your Cytiva equipment.

We provide maintenance and repair services for your AKTA Pilot equipment in Switzerland

Unlike general-purpose service providers, BPMTechCare has in-depth knowledge of the Cytiva (GE Healthcare) ecosystem.
+ Hardware expertise: Maintenance of pumps, selection valves, and UV/Cond/pH sensors.
+ Software expertise: Support for various versions of the UNICORN™ software, essential for the continuity of your purification protocols.

Is your equipment not working properly? Are you seeing a software error message?

Contact us today to schedule service for your AKTA Pure

Quote, free assessment

Why choose our technical service in Switzerland?

Ensure the reliability of your protein purification processes with our specialized maintenance service for AKTA Pure. Based in Switzerland, we offer local technical support to guarantee the accuracy of your chromatography results and the longevity of your FPLC system.

Local Services

Rapid on-site service in Lausanne, Zurich, Basel, or Geneva

Certified Genuine Parts

Use only certified parts to maintain the warranty

FPLC Expertise

Specialists dedicated to Cytiva systems (formerly GE Healthcare)

Customized Maintenance Contracts

À la carte plans or annual maintenance contracts

The Benefits of Preventive Maintenance

Proper maintenance of your AKTA Pure is about more than just preventing breakdowns. It is a strategic investment for your laboratory:

Complete reproducibility

Avoid deviations caused by gradual wear and tear on critical components in your purification batches.

Cost Reduction

Regular maintenance costs much less than a major repair in the event of a breakdown.

Optimal Availability

Minimize the risk of an unplanned shutdown during a critical run or a research campaign.

Our Answers to Your Most Frequently Asked Questions

Maintaining an AKTA Pure chromatography system is a critical task that often raises many technical, logistical, and regulatory questions. Whether you are a lab manager, production engineer, or maintenance technician, you must ensure the continuity of your purification processes without compromising quality. At BPMTechCare, we believe in complete transparency: that’s why we’ve compiled the answers to the most frequently asked questions about the maintenance, troubleshooting, and optimization of your equipment here.

We recommend an annual preventive maintenance visit for an AKTA Pure to address component wear before it becomes critical. This frequency can be adjusted based on how heavily your laboratory uses the equipment.
Yes, our multi-generation expertise covers all AKTA Pure configurations (25, 150, micro), as well as the associated legacy systems.
Yes, in addition to preventive maintenance, we provide responsive corrective support to minimize the impact of any outage on your research or production activities.
Yes, every procedure is fully and certified documented, with complete traceability, in accordance with your laboratory’s regulatory requirements.
Yes, we work with the UNICORN™ software to verify communication with your system, diagnose software errors, and assist you in configuring your methods.
During a standard service, we replace common wear parts (piston seals, check valves, line filters) and verify the calibration of the UV, pH, and conductivity sensors, using manufacturer-certified original parts.
When you choose BPM TechCare, you’re choosing agility and specialized expertise. You’ll benefit from a dedicated point of contact, more competitive rates, and a flexible approach that prioritizes repairing and optimizing your existing equipment over systematic replacement.